Quantitative Analysis of Guanine Nucleotide Exchange Factors (GEFs) as Enzymes

The proteins that possess guanine nucleotide exchange factor (GEF) activity, which include about ~800 G protein coupled receptors (GPCRs),(1) 15 Arf GEFs,(2) 81 Rho GEFs,(3) 8 Ras GEFs,(4) and others for other families of GTPases,(5) catalyze the exchange of GTP for GDP on all regulatory guanine nuc...

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Detalles Bibliográficos
Autores principales: Randazzo, Paul A, Jian, Xiaoying, Chen, Pei-Wen, Zhai, Peng, Soubias, Olivier, Northup, John K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187004/
https://www.ncbi.nlm.nih.gov/pubmed/25332840
http://dx.doi.org/10.4161/cl.27609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187004/
https://www.ncbi.nlm.nih.gov/pubmed/25332840
http://dx.doi.org/10.4161/cl.27609

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