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Synthesis of 2-trifluoromethylpyrazolo[5,1-a]isoquinolines via silver triflate-catalyzed or electrophile-mediated one-pot tandem reaction

An efficient one-pot tandem cyclization/[3 + 2] cycloaddition reaction of N’-(2-alkynylbenzylidene)hydrazides with ethyl 4,4,4-trifluorobut-2-ynoate under silver triflate-catalyzed or electrophile-mediated conditions is described. Various trifluoromethylated pyrazolo[5,1-a]isoquinolines were afforde...

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Detalles Bibliográficos
Autores principales:	Zhou, Xiaoli, Liu, Meiling, Luo, Puying, Lai, Yingjun, Yang, Tangtao, Ding, Qiuping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2014
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187034/ https://www.ncbi.nlm.nih.gov/pubmed/25298796 http://dx.doi.org/10.3762/bjoc.10.238

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