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Quantification of plasma HIV RNA using chemically-engineered peptide nucleic acids
The remarkable stability of peptide nucleic acids (PNAs) toward enzymatic degradation makes this class of molecules ideal to develop as part of a diagnostic device. Here we report the development of chemically-engineered PNAs for the quantitative detection of HIV RNA at clinically relevant levels th...
Autores principales: | Zhao, Chao, Hoppe, Travis, Setty, Mohan Kumar Haleyur Giri, Murray, Danielle, Chun, Tae-Wook, Hewlett, Indira, Appella, Daniel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187110/ https://www.ncbi.nlm.nih.gov/pubmed/25283173 http://dx.doi.org/10.1038/ncomms6079 |
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