A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype

INTRODUCTION: Despite improvements in adjuvant therapy, late systemic recurrences remain a lethal consequence of both early- and late-stage breast cancer. A delayed recurrence is thought to arise from a state of tumor dormancy, but the mechanisms that govern tumor dormancy remain poorly understood....

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Detalles Bibliográficos
Autores principales: Cheng, Qing, Chang, Jeffrey T, Gwin, William R, Zhu, Jun, Ambs, Stefan, Geradts, Joseph, Lyerly, H Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187325/
https://www.ncbi.nlm.nih.gov/pubmed/25060555
http://dx.doi.org/10.1186/s13058-014-0407-9

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