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Multiple sclerosis and pregnancy; What a neurologist may be asked for?

Multiple sclerosis (MS) is the most common chronic autoimmune demyelinating disorder of the central nervous system (CNS) which preferentially involves young women in early child bearing age. Opposite to traditional view emphasized on discouraging female patients from enduring pregnancy, recent inves...

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Detalles Bibliográficos
Autores principales: Siroos, Bahaadin, Harirchian, Mohammad Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Neurological Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187331/
https://www.ncbi.nlm.nih.gov/pubmed/25295147
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author Siroos, Bahaadin
Harirchian, Mohammad Hossein
author_facet Siroos, Bahaadin
Harirchian, Mohammad Hossein
author_sort Siroos, Bahaadin
collection PubMed
description Multiple sclerosis (MS) is the most common chronic autoimmune demyelinating disorder of the central nervous system (CNS) which preferentially involves young women in early child bearing age. Opposite to traditional view emphasized on discouraging female patients from enduring pregnancy, recent investigations showed that pregnancy-related physiological alterations, especially during the third trimester, reduce the annual relapse rate of multiple sclerosis up to 80% which is comparable with conventional disease modifying drugs. Nowadays, expert’s viewpoint is that female patients should not be discouraged from having children. Nonetheless, who and when should be allowed to endure gestational period is a complex decision which should be taken for every patient individually. It necessitates that neurologists be aware of updated information regarding pregnancy-related fetal and maternal considerations in patients with MS. In this brief review, it was tried to discuss this topic according to available data and guideline-based recommendations.
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spelling pubmed-41873312014-10-07 Multiple sclerosis and pregnancy; What a neurologist may be asked for? Siroos, Bahaadin Harirchian, Mohammad Hossein Iran J Neurol Review Article Multiple sclerosis (MS) is the most common chronic autoimmune demyelinating disorder of the central nervous system (CNS) which preferentially involves young women in early child bearing age. Opposite to traditional view emphasized on discouraging female patients from enduring pregnancy, recent investigations showed that pregnancy-related physiological alterations, especially during the third trimester, reduce the annual relapse rate of multiple sclerosis up to 80% which is comparable with conventional disease modifying drugs. Nowadays, expert’s viewpoint is that female patients should not be discouraged from having children. Nonetheless, who and when should be allowed to endure gestational period is a complex decision which should be taken for every patient individually. It necessitates that neurologists be aware of updated information regarding pregnancy-related fetal and maternal considerations in patients with MS. In this brief review, it was tried to discuss this topic according to available data and guideline-based recommendations. Iranian Neurological Association 2014-04-03 /pmc/articles/PMC4187331/ /pubmed/25295147 Text en Copyright © 2014 Iranian Neurological Association, and Tehran University of Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Siroos, Bahaadin
Harirchian, Mohammad Hossein
Multiple sclerosis and pregnancy; What a neurologist may be asked for?
title Multiple sclerosis and pregnancy; What a neurologist may be asked for?
title_full Multiple sclerosis and pregnancy; What a neurologist may be asked for?
title_fullStr Multiple sclerosis and pregnancy; What a neurologist may be asked for?
title_full_unstemmed Multiple sclerosis and pregnancy; What a neurologist may be asked for?
title_short Multiple sclerosis and pregnancy; What a neurologist may be asked for?
title_sort multiple sclerosis and pregnancy; what a neurologist may be asked for?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187331/
https://www.ncbi.nlm.nih.gov/pubmed/25295147
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