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Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice

BACKGROUND: Lipocalin‐2 is a proinflammatory adipokine upregulated in obese humans and animals. A pathogenic role of lipocalin‐2 in hypertension has been suggested. Mice lacking lipocalin‐2 are protected from dietary obesity‐induced cardiovascular dysfunctions. Administration of lipocalin‐2 causes a...

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Detalles Bibliográficos
Autores principales: Song, Erfei, Fan, Pengcheng, Huang, Bosheng, Deng, Han‐Bing, Cheung, Bernard Man Yung, Félétou, Michel, Vilaine, Jean‐Paul, Villeneuve, Nicole, Xu, Aimin, Vanhoutte, Paul M., Wang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187505/
https://www.ncbi.nlm.nih.gov/pubmed/24721803
http://dx.doi.org/10.1161/JAHA.114.000837