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Pharmacokinetic Interaction between Pyronaridine-Artesunate and Metoprolol

The objectives of this study were to characterize any drug-drug interaction between the antimalarial Pyramax (pyronaridine-artesunate [PA]) and the CYP2D6 probe substrate metoprolol and to assess the safety of 60-day or 90-day PA redosing, particularly with regard to liver biochemistry parameters. H...

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Detalles Bibliográficos
Autores principales:	Morris, Carrie A., Pokorny, Rolf, Lopez-Lazaro, Luis, Miller, Robert M., Arbe-Barnes, Sarah, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Shin, Jang-Sik, Fleckenstein, Lawrence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2014
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187956/ https://www.ncbi.nlm.nih.gov/pubmed/25070091 http://dx.doi.org/10.1128/AAC.02716-14

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