The contribution of cell surface FcRn in monoclonal antibody serum uptake from the intestine in suckling rat pups

The neonatal Fc receptor (FcRn) in intestinal epithelium is the primary mechanism for transfer of maternal immunoglobulin G (IgG) from suckled milk to serum; but the factors contributing to the rapid uptake of IgG are poorly understood. These studies help to determine the contribution of cell surfac...

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Detalles Bibliográficos
Autores principales: Cooper, Philip R., Kliwinski, Connie M., Perkinson, Robert A., Ragwan, Edwin, Mabus, John R., Powers, Gordon D., Dorai, Haimanti, Giles-Komar, Jill, Hornby, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188031/
https://www.ncbi.nlm.nih.gov/pubmed/25339905
http://dx.doi.org/10.3389/fphar.2014.00225

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