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Sexual Dimorphism in the Effects of Exercise on Metabolism of Lipids to Support Resting Metabolism
Exercise training is generally a healthful activity and an effective intervention for reducing the risk of numerous chronic diseases including cardiovascular disease and diabetes. This is likely both a result of prevention of weight gain over time and direct effects of exercise on metabolism of lipi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188128/ https://www.ncbi.nlm.nih.gov/pubmed/25339941 http://dx.doi.org/10.3389/fendo.2014.00162 |
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author | Henderson, Gregory C. |
author_facet | Henderson, Gregory C. |
author_sort | Henderson, Gregory C. |
collection | PubMed |
description | Exercise training is generally a healthful activity and an effective intervention for reducing the risk of numerous chronic diseases including cardiovascular disease and diabetes. This is likely both a result of prevention of weight gain over time and direct effects of exercise on metabolism of lipids and the other macronutrient classes. Importantly, a single bout of exercise can alter lipid metabolism and metabolic rate for hours and even into the day following exercise, so individuals who regularly exercise, even if not performed every single day, overall could experience a substantial change in their resting metabolism that would reduce risk for metabolic diseases. However, resting metabolism does not respond similarly in all individuals to exercise participation, and indeed gender or sex is a major determinant of the response of resting lipid metabolism to prior exercise. In order to fully appreciate the metabolic effects and health benefits of exercise, the differences between men and women must be considered. In this article, the differences in the effects of exercise on resting metabolic rate, fuel selection after exercise, as well as the shuttling of triglyceride and fatty acids between tissues are discussed. Furthermore, concepts related to sex differences in the precision of homeostatic control and sex differences in the integration of metabolism between various organs are considered. |
format | Online Article Text |
id | pubmed-4188128 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-41881282014-10-22 Sexual Dimorphism in the Effects of Exercise on Metabolism of Lipids to Support Resting Metabolism Henderson, Gregory C. Front Endocrinol (Lausanne) Endocrinology Exercise training is generally a healthful activity and an effective intervention for reducing the risk of numerous chronic diseases including cardiovascular disease and diabetes. This is likely both a result of prevention of weight gain over time and direct effects of exercise on metabolism of lipids and the other macronutrient classes. Importantly, a single bout of exercise can alter lipid metabolism and metabolic rate for hours and even into the day following exercise, so individuals who regularly exercise, even if not performed every single day, overall could experience a substantial change in their resting metabolism that would reduce risk for metabolic diseases. However, resting metabolism does not respond similarly in all individuals to exercise participation, and indeed gender or sex is a major determinant of the response of resting lipid metabolism to prior exercise. In order to fully appreciate the metabolic effects and health benefits of exercise, the differences between men and women must be considered. In this article, the differences in the effects of exercise on resting metabolic rate, fuel selection after exercise, as well as the shuttling of triglyceride and fatty acids between tissues are discussed. Furthermore, concepts related to sex differences in the precision of homeostatic control and sex differences in the integration of metabolism between various organs are considered. Frontiers Media S.A. 2014-10-07 /pmc/articles/PMC4188128/ /pubmed/25339941 http://dx.doi.org/10.3389/fendo.2014.00162 Text en Copyright © 2014 Henderson. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Endocrinology Henderson, Gregory C. Sexual Dimorphism in the Effects of Exercise on Metabolism of Lipids to Support Resting Metabolism |
title | Sexual Dimorphism in the Effects of Exercise on Metabolism of Lipids to Support Resting Metabolism |
title_full | Sexual Dimorphism in the Effects of Exercise on Metabolism of Lipids to Support Resting Metabolism |
title_fullStr | Sexual Dimorphism in the Effects of Exercise on Metabolism of Lipids to Support Resting Metabolism |
title_full_unstemmed | Sexual Dimorphism in the Effects of Exercise on Metabolism of Lipids to Support Resting Metabolism |
title_short | Sexual Dimorphism in the Effects of Exercise on Metabolism of Lipids to Support Resting Metabolism |
title_sort | sexual dimorphism in the effects of exercise on metabolism of lipids to support resting metabolism |
topic | Endocrinology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188128/ https://www.ncbi.nlm.nih.gov/pubmed/25339941 http://dx.doi.org/10.3389/fendo.2014.00162 |
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