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A Randomized Controlled Trial of Angiotensin-Converting Enzyme Inhibition for Skeletal Muscle Dysfunction in COPD
BACKGROUND: Skeletal muscle impairment is a recognized complication of COPD, predicting mortality in severe disease. Increasing evidence implicates the renin-angiotensin system in control of muscle phenotype. We hypothesized that angiotensin-converting enzyme (ACE) inhibition would improve quadricep...
Autores principales: | Shrikrishna, Dinesh, Tanner, Rebecca J., Lee, Jen Y., Natanek, Amanda, Lewis, Amy, Murphy, Patrick B., Hart, Nicholas, Moxham, John, Montgomery, Hugh E., Kemp, Paul R., Polkey, Michael I., Hopkinson, Nicholas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American College of Chest Physicians
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188149/ https://www.ncbi.nlm.nih.gov/pubmed/24556825 http://dx.doi.org/10.1378/chest.13-2483 |
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