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Kinetic Analysis of Lauric Acid Hydroxylation by Human Cytochrome P450 4A11

[Image: see text] Cytochrome P450 (P450) 4A11 is the only functionally active subfamily 4A P450 in humans. P450 4A11 catalyzes mainly ω-hydroxylation of fatty acids in liver and kidney; this process is not a major degradative pathway, but at least one product, 20-hydroxyeicosatetraenoic acid, has im...

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Detalles Bibliográficos
Autores principales:	Kim, Donghak, Cha, Gun-Su, Nagy, Leslie D., Yun, Chul-Ho, Guengerich, F. Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188250/ https://www.ncbi.nlm.nih.gov/pubmed/25203493 http://dx.doi.org/10.1021/bi500710e

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