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Centromere-Independent Accumulation of Cohesin at Ectopic Heterochromatin Sites Induces Chromosome Stretching during Anaphase
Pericentric heterochromatin, while often considered as “junk” DNA, plays important functions in chromosome biology. It contributes to sister chromatid cohesion, a process mediated by the cohesin complex that ensures proper genome segregation during nuclear division. Long stretches of heterochromatin...
Autores principales: | Oliveira, Raquel A., Kotadia, Shaila, Tavares, Alexandra, Mirkovic, Mihailo, Bowlin, Katherine, Eichinger, Christian S., Nasmyth, Kim, Sullivan, William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188515/ https://www.ncbi.nlm.nih.gov/pubmed/25290697 http://dx.doi.org/10.1371/journal.pbio.1001962 |
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