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Regulator of G-Protein Signaling-5 Is a Marker of Hepatic Stellate Cells and Expression Mediates Response to Liver Injury
Liver fibrosis is mediated by hepatic stellate cells (HSCs), which respond to a variety of cytokine and growth factors to moderate the response to injury and create extracellular matrix at the site of injury. G-protein coupled receptor (GPCR)-mediated signaling, via endothelin-1 (ET-1) and angiotens...
Autores principales: | Bahrami, Arya J., Gunaje, Jagadambika J., Hayes, Brian J., Riehle, Kimberly J., Kenerson, Heidi L., Yeung, Raymond S., Stempien-Otero, April S., Campbell, Jean S., Mahoney, William M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188519/ https://www.ncbi.nlm.nih.gov/pubmed/25290689 http://dx.doi.org/10.1371/journal.pone.0108505 |
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