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Lysosomal drug sequestration as a mechanism of drug resistance in vascular sarcoma cells marked by high CSF-1R expression

BACKGROUND: Human angiosarcoma and canine hemangiosarcoma are thought to arise from vascular tissue or vascular forming cells based upon their histological appearance. However, recent evidence indicates a hematopoietic or angioblastic cell of origin for these tumors. In support of this idea, we prev...

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Detalles Bibliográficos
Autores principales: Gorden, Brandi H, Saha, Jhuma, Khammanivong, Ali, Schwartz, Gary K, Dickerson, Erin B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188569/
https://www.ncbi.nlm.nih.gov/pubmed/25295160
http://dx.doi.org/10.1186/2045-824X-6-20

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