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Polyomavirus-Associated Trichodysplasia Spinulosa Involves Hyperproliferation, pRB Phosphorylation and Upregulation of p16 and p21

Trichodysplasia spinulosa (TS) is a proliferative skin disease observed in severely immunocompromized patients. It is characterized by papule and trichohyalin-rich spicule formation, epidermal acanthosis and distention of dysmorphic hair follicles overpopulated by inner root sheath cells (IRS). TS p...

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Detalles Bibliográficos
Autores principales: Kazem, Siamaque, van der Meijden, Els, Wang, Richard C., Rosenberg, Arlene S., Pope, Elena, Benoit, Taylor, Fleckman, Philip, Feltkamp, Mariet C. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188587/
https://www.ncbi.nlm.nih.gov/pubmed/25291363
http://dx.doi.org/10.1371/journal.pone.0108947