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Extended Exenatide Administration Enhances Lipid Metabolism and Exacerbates Pancreatic Injury in Mice on a High Fat, High Carbohydrate Diet

This study expanded upon a previous study in mice reporting a link between exenatide treatment and exocrine pancreatic injury by demonstrating temporal and dose responses and providing an initial mechanistic hypothesis. The design of the present study included varying lengths of exenatide exposure (...

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Detalles Bibliográficos
Autores principales: Rouse, Rodney, Zhang, Leshuai, Shea, Katherine, Zhou, Hongfei, Xu, Lin, Stewart, Sharron, Rosenzweig, Barry, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188617/
https://www.ncbi.nlm.nih.gov/pubmed/25291183
http://dx.doi.org/10.1371/journal.pone.0109477