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Human Adenovirus-Specific γ/δ and CD8(+) T Cells Generated by T-Cell Receptor Transfection to Treat Adenovirus Infection after Allogeneic Stem Cell Transplantation
Human adenovirus infection is life threatening after allogeneic haematopoietic stem cell transplantation (HSCT). Immunotherapy with donor-derived adenovirus-specific T cells is promising; however, 20% of all donors lack adenovirus-specific T cells. To overcome this, we transfected α/β T cells with m...
Autores principales: | Dörrie, Jan, Krug, Christian, Hofmann, Christian, Müller, Ina, Wellner, Verena, Knippertz, Ilka, Schierer, Stephan, Thomas, Simone, Zipperer, Elke, Printz, Dieter, Fritsch, Gerhard, Schuler, Gerold, Schaft, Niels, Geyeregger, Rene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188623/ https://www.ncbi.nlm.nih.gov/pubmed/25289687 http://dx.doi.org/10.1371/journal.pone.0109944 |
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