Cargando…

Cohesin’s ATPase Activity Couples Cohesin Loading onto DNA with Smc3 Acetylation

BACKGROUND: Cohesin mediates sister chromatid cohesion by topologically entrapping sister DNA molecules inside its ring structure. Cohesin is loaded onto DNA by the Scc2/NIPBL-Scc4/MAU2-loading complex in a manner that depends on the adenosine triphosphatase (ATPase) activity of cohesin’s Smc1 and S...

Descripción completa

Detalles Bibliográficos
Autores principales: Ladurner, Rene, Bhaskara, Venugopal, Huis in ’t Veld, Pim J., Davidson, Iain F., Kreidl, Emanuel, Petzold, Georg, Peters, Jan-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188815/
https://www.ncbi.nlm.nih.gov/pubmed/25220052
http://dx.doi.org/10.1016/j.cub.2014.08.011

Ejemplares similares