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Top-down Proteomics Reveals Concerted Reductions in Myofilament and Z-disc Protein Phosphorylation after Acute Myocardial Infarction

Heart failure (HF) is a leading cause of morbidity and mortality worldwide and is most often precipitated by myocardial infarction. However, the molecular changes driving cardiac dysfunction immediately after myocardial infarction remain poorly understood. Myofilament proteins, responsible for cardi...

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Detalles Bibliográficos
Autores principales: Peng, Ying, Gregorich, Zachery R., Valeja, Santosh G., Zhang, Han, Cai, Wenxuan, Chen, Yi-Chen, Guner, Huseyin, Chen, Albert J., Schwahn, Denise J., Hacker, Timothy A., Liu, Xiaowen, Ge, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189000/
https://www.ncbi.nlm.nih.gov/pubmed/24969035
http://dx.doi.org/10.1074/mcp.M114.040675