Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation

BACKGROUND: DNA methylation is an important type of epigenetic modification involved in gene regulation. Although strong DNA methylation at promoters is widely recognized to be associated with transcriptional repression, many aspects of DNA methylation remain not fully understood, including the quan...

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Detalles Bibliográficos
Autores principales: Lou, Shaoke, Lee, Heung-Man, Qin, Hao, Li, Jing-Woei, Gao, Zhibo, Liu, Xin, Chan, Landon L, KL Lam, Vincent, So, Wing-Yee, Wang, Ying, Lok, Si, Wang, Jun, Ma, Ronald CW, Tsui, Stephen Kwok-Wing, Chan, Juliana CN, Chan, Ting-Fung, Yip, Kevin Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189148/
https://www.ncbi.nlm.nih.gov/pubmed/25074712
http://dx.doi.org/10.1186/s13059-014-0408-0

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