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In vitro assessment of antitumor activities of the PI3K/mTOR inhibitor GSK2126458

BACKGROUND: Up-regulation of the PI3K/mTOR (phosphatidylinositol-3′ kinase/mammalian target of rapamycin) signaling is common in carcinoma. Consistently, targeting these molecules has been shown to halt the growth of many tumors. The main purpose of this study was to develop surrogate biomarkers of...

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Detalles Bibliográficos
Autores principales:	Albawardi, Alia, Al Ayyan, Muna, Al Bashir, Mohamed, Souid, Abdul-Kader, Almarzooqi, Saeeda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189195/ https://www.ncbi.nlm.nih.gov/pubmed/25298748 http://dx.doi.org/10.1186/s12935-014-0090-z

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