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Comparison of cardiovascular co-morbidities and CPAP use in patients with positional and non-positional mild obstructive sleep apnea

BACKGROUND: This retrospective cohort study aimed to determine if there are differences in cardiovascular co-morbidities, blood pressure (BP) and continuous positive airway pressure (CPAP) use between patients with positional-dependent and nonpositional-dependent obstructive sleep apnea (OSA). METHO...

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Autores principales: Huang, Yi-Chih, Lin, Chun-Yao, Lan, Chou-Chin, Wu, Yao-Kuang, Lim, Chor-Shen, Huang, Chun-Yao, Huang, Hsuan-Li, Yeh, Kuan-Hung, Liu, Yu-Chih, Yang, Mei-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189203/
https://www.ncbi.nlm.nih.gov/pubmed/25257571
http://dx.doi.org/10.1186/1471-2466-14-153
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author Huang, Yi-Chih
Lin, Chun-Yao
Lan, Chou-Chin
Wu, Yao-Kuang
Lim, Chor-Shen
Huang, Chun-Yao
Huang, Hsuan-Li
Yeh, Kuan-Hung
Liu, Yu-Chih
Yang, Mei-Chen
author_facet Huang, Yi-Chih
Lin, Chun-Yao
Lan, Chou-Chin
Wu, Yao-Kuang
Lim, Chor-Shen
Huang, Chun-Yao
Huang, Hsuan-Li
Yeh, Kuan-Hung
Liu, Yu-Chih
Yang, Mei-Chen
author_sort Huang, Yi-Chih
collection PubMed
description BACKGROUND: This retrospective cohort study aimed to determine if there are differences in cardiovascular co-morbidities, blood pressure (BP) and continuous positive airway pressure (CPAP) use between patients with positional-dependent and nonpositional-dependent obstructive sleep apnea (OSA). METHODS: Patients who were referred for overnight polysomnography for suspected OSA between 2007 and 2011 were screened. A total of 371 patients with OSA were included for analysis and divided into six groups according to positional-dependency and severity of OSA: positional mild (n = 52), positional moderate (n = 29), positional severe (n = 24), non-positional mild (n = 18), non-positional moderate (n = 70) and non-positional severe group (n = 178). The six groups were compared for anthropometric and polysomnographic variables, presence of cardiovascular co-morbidities, morning and evening BP and the changes between evening and morning BP, and CPAP device usage patterns. RESULTS: Demographic and anthropometric variables showed non-positional severe OSA had poor sleep quality and higher morning blood pressures. Positional mild OSA had the lowest cardiovascular co-morbidities. Overall CPAP acceptance was 45.6%. Mild OSA patients had the lowest CPAP acceptance rate (10%), followed by moderate group (37.37%) and severe group (61.88%, P < 0.001). However, the significant difference in CPAP acceptance across OSA severity disappeared when the data was stratified by positional dependency. CONCLUSIONS: This study found that positional mild OSA had less cardiovascular co-morbidities compared with subjects with positional severe OSA. Independent of posture, CPAP acceptance in patients with mild OSA was low, but CPAP compliance was similar in CPAP acceptors regardless of posture dependency of OSA. Since there are increasing evidences of greater cardiovascular risk for untreated mild OSA, improving CPAP acceptance among mild OSA patients may be clinically important regardless of posture dependency.
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spelling pubmed-41892032014-10-09 Comparison of cardiovascular co-morbidities and CPAP use in patients with positional and non-positional mild obstructive sleep apnea Huang, Yi-Chih Lin, Chun-Yao Lan, Chou-Chin Wu, Yao-Kuang Lim, Chor-Shen Huang, Chun-Yao Huang, Hsuan-Li Yeh, Kuan-Hung Liu, Yu-Chih Yang, Mei-Chen BMC Pulm Med Research Article BACKGROUND: This retrospective cohort study aimed to determine if there are differences in cardiovascular co-morbidities, blood pressure (BP) and continuous positive airway pressure (CPAP) use between patients with positional-dependent and nonpositional-dependent obstructive sleep apnea (OSA). METHODS: Patients who were referred for overnight polysomnography for suspected OSA between 2007 and 2011 were screened. A total of 371 patients with OSA were included for analysis and divided into six groups according to positional-dependency and severity of OSA: positional mild (n = 52), positional moderate (n = 29), positional severe (n = 24), non-positional mild (n = 18), non-positional moderate (n = 70) and non-positional severe group (n = 178). The six groups were compared for anthropometric and polysomnographic variables, presence of cardiovascular co-morbidities, morning and evening BP and the changes between evening and morning BP, and CPAP device usage patterns. RESULTS: Demographic and anthropometric variables showed non-positional severe OSA had poor sleep quality and higher morning blood pressures. Positional mild OSA had the lowest cardiovascular co-morbidities. Overall CPAP acceptance was 45.6%. Mild OSA patients had the lowest CPAP acceptance rate (10%), followed by moderate group (37.37%) and severe group (61.88%, P < 0.001). However, the significant difference in CPAP acceptance across OSA severity disappeared when the data was stratified by positional dependency. CONCLUSIONS: This study found that positional mild OSA had less cardiovascular co-morbidities compared with subjects with positional severe OSA. Independent of posture, CPAP acceptance in patients with mild OSA was low, but CPAP compliance was similar in CPAP acceptors regardless of posture dependency of OSA. Since there are increasing evidences of greater cardiovascular risk for untreated mild OSA, improving CPAP acceptance among mild OSA patients may be clinically important regardless of posture dependency. BioMed Central 2014-09-26 /pmc/articles/PMC4189203/ /pubmed/25257571 http://dx.doi.org/10.1186/1471-2466-14-153 Text en © Huang et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Research Article
Huang, Yi-Chih
Lin, Chun-Yao
Lan, Chou-Chin
Wu, Yao-Kuang
Lim, Chor-Shen
Huang, Chun-Yao
Huang, Hsuan-Li
Yeh, Kuan-Hung
Liu, Yu-Chih
Yang, Mei-Chen
Comparison of cardiovascular co-morbidities and CPAP use in patients with positional and non-positional mild obstructive sleep apnea
title Comparison of cardiovascular co-morbidities and CPAP use in patients with positional and non-positional mild obstructive sleep apnea
title_full Comparison of cardiovascular co-morbidities and CPAP use in patients with positional and non-positional mild obstructive sleep apnea
title_fullStr Comparison of cardiovascular co-morbidities and CPAP use in patients with positional and non-positional mild obstructive sleep apnea
title_full_unstemmed Comparison of cardiovascular co-morbidities and CPAP use in patients with positional and non-positional mild obstructive sleep apnea
title_short Comparison of cardiovascular co-morbidities and CPAP use in patients with positional and non-positional mild obstructive sleep apnea
title_sort comparison of cardiovascular co-morbidities and cpap use in patients with positional and non-positional mild obstructive sleep apnea
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189203/
https://www.ncbi.nlm.nih.gov/pubmed/25257571
http://dx.doi.org/10.1186/1471-2466-14-153
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