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Dysregulation of genome-wide gene expression and DNA methylation in abnormal cloned piglets
BACKGROUND: Epigenetic modifications (especially altered DNA methylation) resulting in altered gene expression may be one reason for development failure or abnormalities in cloned animals, but the underlying mechanism of the abnormal phenotype in cloned piglets remains unknown. Some cloned piglets i...
Autores principales: | Li, Guanglei, Jia, Qitao, Zhao, Jianguo, Li, Xinyun, Yu, Mei, Samuel, Melissa S, Zhao, Shuhong, Prather, Randall S, Li, Changchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189204/ https://www.ncbi.nlm.nih.gov/pubmed/25253444 http://dx.doi.org/10.1186/1471-2164-15-811 |
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