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Activity of right premotor-parietal regions dependent upon imagined force level: an fMRI study

In this study, we utilized functional magnetic resonance imaging (fMRI) to measure blood oxygenation level-dependent (BOLD) signals. This allowed us to evaluate the relationship between brain activity and imagined force level. Subjects performed motor imagery of repetitive right hand grasping with t...

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Autores principales: Mizuguchi, Nobuaki, Nakata, Hiroki, Kanosue, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189331/
https://www.ncbi.nlm.nih.gov/pubmed/25339893
http://dx.doi.org/10.3389/fnhum.2014.00810
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author Mizuguchi, Nobuaki
Nakata, Hiroki
Kanosue, Kazuyuki
author_facet Mizuguchi, Nobuaki
Nakata, Hiroki
Kanosue, Kazuyuki
author_sort Mizuguchi, Nobuaki
collection PubMed
description In this study, we utilized functional magnetic resonance imaging (fMRI) to measure blood oxygenation level-dependent (BOLD) signals. This allowed us to evaluate the relationship between brain activity and imagined force level. Subjects performed motor imagery of repetitive right hand grasping with three different levels of contractile force; 10%, 30%, and 60% of their maximum voluntary contraction (MVC). We observed a common activation among each condition in the following brain regions; the dorsolateral prefrontal cortex (DLPFC), ventrolateral prefrontal cortex (VLPFC), supplementary motor area (SMA), premotor area (PM), insula, and inferior parietal lobule (IPL). In addition, the BOLD signal changes were significantly larger at 60% MVC than at 10% MVC in the right PM, the right IPL, and the primary somatosensory cortex (SI). These findings indicate that during motor imagery right fronto-parietal activity increases as the imagined contractile force level is intensified. The present finding that the right brain activity during motor imagery is clearly altered depending on the imagined force level suggests that it may be possible to decode intended force level during the motor imagery of patients or healthy subjects.
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spelling pubmed-41893312014-10-22 Activity of right premotor-parietal regions dependent upon imagined force level: an fMRI study Mizuguchi, Nobuaki Nakata, Hiroki Kanosue, Kazuyuki Front Hum Neurosci Neuroscience In this study, we utilized functional magnetic resonance imaging (fMRI) to measure blood oxygenation level-dependent (BOLD) signals. This allowed us to evaluate the relationship between brain activity and imagined force level. Subjects performed motor imagery of repetitive right hand grasping with three different levels of contractile force; 10%, 30%, and 60% of their maximum voluntary contraction (MVC). We observed a common activation among each condition in the following brain regions; the dorsolateral prefrontal cortex (DLPFC), ventrolateral prefrontal cortex (VLPFC), supplementary motor area (SMA), premotor area (PM), insula, and inferior parietal lobule (IPL). In addition, the BOLD signal changes were significantly larger at 60% MVC than at 10% MVC in the right PM, the right IPL, and the primary somatosensory cortex (SI). These findings indicate that during motor imagery right fronto-parietal activity increases as the imagined contractile force level is intensified. The present finding that the right brain activity during motor imagery is clearly altered depending on the imagined force level suggests that it may be possible to decode intended force level during the motor imagery of patients or healthy subjects. Frontiers Media S.A. 2014-10-08 /pmc/articles/PMC4189331/ /pubmed/25339893 http://dx.doi.org/10.3389/fnhum.2014.00810 Text en Copyright © 2014 Mizuguchi, Nakata and Kanosue. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Mizuguchi, Nobuaki
Nakata, Hiroki
Kanosue, Kazuyuki
Activity of right premotor-parietal regions dependent upon imagined force level: an fMRI study
title Activity of right premotor-parietal regions dependent upon imagined force level: an fMRI study
title_full Activity of right premotor-parietal regions dependent upon imagined force level: an fMRI study
title_fullStr Activity of right premotor-parietal regions dependent upon imagined force level: an fMRI study
title_full_unstemmed Activity of right premotor-parietal regions dependent upon imagined force level: an fMRI study
title_short Activity of right premotor-parietal regions dependent upon imagined force level: an fMRI study
title_sort activity of right premotor-parietal regions dependent upon imagined force level: an fmri study
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189331/
https://www.ncbi.nlm.nih.gov/pubmed/25339893
http://dx.doi.org/10.3389/fnhum.2014.00810
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