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α-Mangostin from Cratoxylum arborescens demonstrates apoptogenesis in MCF-7 with regulation of NF-κB and Hsp70 protein modulation in vitro, and tumor reduction in vivo

Cratoxylum arborescens is an equatorial plant belonging to the family Guttiferae. In the current study, α-Mangostin (AM) was isolated and its cell death mechanism was studied. HCS was undertaken to detect the nuclear condensation, mitochondrial membrane potential, cell permeability, and the release...

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Detalles Bibliográficos
Autores principales: Ibrahim, Mohamed Yousif, Hashim, Najihah Mohd, Mohan, Syam, Abdulla, Mahmood Ameen, Kamalidehghan, Behnam, Ghaderian, Mostafa, Dehghan, Firouzeh, Ali, Landa Zeenelabdin, Arbab, Ismail Adam, Yahayu, Maizatulakmal, Lian, Gwendoline Ee Cheng, Ahmadipour, Fatemeh, Ali, Hapipah Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189707/
https://www.ncbi.nlm.nih.gov/pubmed/25302018
http://dx.doi.org/10.2147/DDDT.S66105