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An optimized probucol microencapsulated formulation integrating a secondary bile acid (deoxycholic acid) as a permeation enhancer
The authors have previously designed, developed, and characterized a novel microencapsulated formulation as a platform for the targeted delivery of therapeutics in an animal model of type 2 diabetes, using the drug probucol (PB). The aim of this study was to optimize PB microcapsules by incorporatin...
Autores principales: | Mooranian, Armin, Negrulj, Rebecca, Chen-Tan, Nigel, Watts, Gerald F, Arfuso, Frank, Al-Salami, Hani |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189710/ https://www.ncbi.nlm.nih.gov/pubmed/25302020 http://dx.doi.org/10.2147/DDDT.S68247 |
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