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Protective Role of 5-Lipoxigenase during Leishmania infantum Infection Is Associated with Th17 Subset

Visceral leishmaniasis (VL) is a chronic and fatal disease caused by Leishmania infantum in Brazil. Leukocyte recruitment to infected tissue is a crucial event for the control of infections such as VL. Leucotriens are lipid mediators synthesized by 5-lipoxygenase (5-LO) and they display a protective...

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Detalles Bibliográficos
Autores principales: Sacramento, Laís Amorim, Cunha, Fernando Q., de Almeida, Roque Pacheco, da Silva, João Santana, Carregaro, Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189762/
https://www.ncbi.nlm.nih.gov/pubmed/25309905
http://dx.doi.org/10.1155/2014/264270