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High-throughput optical screening of cellular mechanotransduction

We introduce an optical platform for rapid, high-throughput screening of exogenous molecules that affect cellular mechanotransduction. Our method initiates mechanotransduction in adherent cells using single laser-microbeam generated micro-cavitation bubbles (μCBs) without requiring flow chambers or...

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Detalles Bibliográficos
Autores principales: Compton, Jonathan L., Luo, Justin C., Ma, Huan, Botvinick, Elliot, Venugopalan, Vasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189826/
https://www.ncbi.nlm.nih.gov/pubmed/25309621
http://dx.doi.org/10.1038/nphoton.2014.165