Cargando…

Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies

BACKGROUND: The epilepsies are a clinically heterogeneous group of neurological disorders. Despite strong evidence for heritability, genome-wide association studies have had little success in identification of risk loci associated with epilepsy, probably because of relatively small sample sizes and...

Descripción completa

Detalles Bibliográficos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lancet Pub. Group 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189926/ https://www.ncbi.nlm.nih.gov/pubmed/25087078 http://dx.doi.org/10.1016/S1474-4422(14)70171-1

Ejemplares similares

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study
por: Kasperavičiūtė, Dalia, et al.
Publicado: (2010)

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis
por: Rhodes, Christopher J, et al.
Publicado: (2019)

Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta-Analysis of Three Genome-Wide Association Studies
por: Nolte, Ilja M., et al.
Publicado: (2009)

Genome-wide association studies and genetic architecture of common human diseases
por: Montgomery, Grant W
Publicado: (2011)

Association of common genetic variants with brain microbleeds: A genome-wide association study
por: Knol, Maria J., et al.
Publicado: (2020)

Genome Wide Meta-Analysis identifies common genetic signatures shared by heart function and Alzheimer’s disease
por: Sáez, M. E., et al.
Publicado: (2019)

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
Publicado: (2018)

Genome-Wide Meta-Analysis Identifies Two Novel Risk Loci for Epilepsy
por: Song, Meng, et al.
Publicado: (2021)

A Genome Wide Meta-Analysis Study for Identification of Common Variation Associated with Breast Cancer Prognosis
por: Rafiq, Sajjad, et al.
Publicado: (2014)

Genome-wide association analysis of idiopathic epilepsy in the Belgian shepherd
por: Belanger, J. M., et al.
Publicado: (2020)

Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake(1)(2)(3)(4)
por: Tanaka, Toshiko, et al.
Publicado: (2013)

Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking
por: Terracciano, A, et al.
Publicado: (2011)

Genetic Factors for Coronary Heart Disease and Their Mechanisms: A Meta-Analysis and Comprehensive Review of Common Variants from Genome-Wide Association Studies
por: Zarkasi, Khairul Anwar, et al.
Publicado: (2022)

Genome-Wide Association Study to Identify Common Variants Associated with Brachial Circumference: A Meta-Analysis of 14 Cohorts
por: Boraska, Vesna, et al.
Publicado: (2012)

Genome-Wide Association Studies: Progress in Identifying Genetic Biomarkers in Common, Complex Diseases
por: Kingsmore, Stephen F., et al.
Publicado: (2007)

Using common genetic variants to find drugs for common epilepsies
por: Mirza, Nasir, et al.
Publicado: (2021)

Genetic architecture of common bunt resistance in winter wheat using genome-wide association study
por: Mourad, Amira M. I., et al.
Publicado: (2018)

Genome-wide analysis of differential RNA editing in epilepsy
por: Srivastava, Prashant Kumar, et al.
Publicado: (2017)

Meta-analysis of genome-wide association studies provides insights into genetic control of tomato flavor
por: Zhao, Jiantao, et al.
Publicado: (2019)

Genome‐wide association study: Exploring the genetic basis for responsiveness to ketogenic dietary therapies for drug‐resistant epilepsy
por: Schoeler, Natasha E., et al.
Publicado: (2018)

Genome-wide meta-analysis of common variant differences between men and women
por: Boraska, Vesna, et al.
Publicado: (2012)

Genome-Wide Association Analysis of Grain Hardness in Common Wheat
por: He, Xianfang, et al.
Publicado: (2023)

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
por: Wheeler, Eleanor, et al.
Publicado: (2017)

What Can Genome-Wide Association Studies Tell Us about the Genetics of Common Disease
por: Iles, Mark M
Publicado: (2008)

Genome-wide association studies dissect the genetic architecture of seed shape and size in common bean
por: Giordani, Willian, et al.
Publicado: (2022)

Genome-wide association studies provide insights into the genetic determination of fruit traits of pear
por: Zhang, Ming-Yue, et al.
Publicado: (2021)

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium
por: van den Berg, Stéphanie M., et al.
Publicado: (2015)

Genome-Wide Association Study to Identify the Genetic Determinants of Otitis Media Susceptibility in Childhood
por: Rye, Marie S., et al.
Publicado: (2012)

Genome-wide association study reveals the genetic determinism of serum biochemical indicators in ducks
por: Tang, Hehe, et al.
Publicado: (2022)

The role of common genetic variation in presumed monogenic epilepsies
por: Campbell, Ciarán, et al.
Publicado: (2022)

Genetic Determinants of Cardiovascular Events among Women with Migraine: A Genome-Wide Association Study
por: Schürks, Markus, et al.
Publicado: (2011)

Genetic determinants of metabolism in health and disease: from biochemical genetics to genome-wide associations
por: Robinette, Steven L, et al.
Publicado: (2012)

Beyond Genome-Wide Association Studies: New Strategies for Identifying Genetic Determinants of Hypertension
por: Wang, Xiaoling, et al.
Publicado: (2011)

Meta-analysis of genome-wide association studies of anxiety disorders
por: Otowa, Takeshi, et al.
Publicado: (2016)

A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome?
por: Fungtammasan, Arkarachai, et al.
Publicado: (2012)

A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations
por: Wang, Xu, et al.
Publicado: (2012)

Analysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy
por: Schijven, Dick, et al.
Publicado: (2020)

Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure
por: Levin, Michael G., et al.
Publicado: (2022)

The Impact of Imputation on Meta-Analysis of Genome-Wide Association Studies
por: Li, Jian, et al.
Publicado: (2012)

Meta-analysis of sex-specific genome-wide association studies
por: Magi, Reedik, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_tchmg8dgcvoubapmesbq7mvolf