Astaxanthin Inhibits JAK/STAT-3 Signaling to Abrogate Cell Proliferation, Invasion and Angiogenesis in a Hamster Model of Oral Cancer

Identifying agents that inhibit STAT-3, a cytosolic transcription factor involved in the activation of various genes implicated in tumour progression is a promising strategy for cancer chemoprevention. In the present study, we investigated the effect of dietary astaxanthin on JAK-2/STAT-3 signaling...

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Detalles Bibliográficos
Autores principales: Kowshik, J., Baba, Abdul Basit, Giri, Hemant, Deepak Reddy, G., Dixit, Madhulika, Nagini, Siddavaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189964/
https://www.ncbi.nlm.nih.gov/pubmed/25296162
http://dx.doi.org/10.1371/journal.pone.0109114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189964/
https://www.ncbi.nlm.nih.gov/pubmed/25296162
http://dx.doi.org/10.1371/journal.pone.0109114

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