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Carnitine Palmitoyltransferase 1b Deficiency Protects Mice from Diet-Induced Insulin Resistance
BACKGROUND: Carnitine Palmitoyl Transferase 1 (CPT1) is the rate-limiting enzyme governing long-chain fatty acid entry into mitochondria. CPT1 inhibitors have been developed and exhibited beneficial effects against type II diabetes in short-term preclinical animal studies. However, the long-term eff...
Autores principales: | Kim, Teayoun, He, Lan, Johnson, Maria S., Li, Yan, Zeng, Ling, Ding, Yishu, Long, Qinqiang, Moore, John F., Sharer, Jon D., Nagy, Tim R., Young, Martin E., Wood, Philip A., Yang, Qinglin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190034/ https://www.ncbi.nlm.nih.gov/pubmed/25309812 http://dx.doi.org/10.4172/2155-6156.1000361 |
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