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Differential Expression of microRNAs in Francisella tularensis-Infected Human Macrophages: miR-155-Dependent Downregulation of MyD88 Inhibits the Inflammatory Response

Francisella tularensis is a Gram-negative, facultative intracellular pathogen that replicates in the cytosol of macrophages and is the causative agent of the potentially fatal disease tularemia. A characteristic feature of F. tularensis is its limited proinflammatory capacity, but the mechanisms tha...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Sarmistha, Long, Matthew E., Allen, Lee-Ann H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190180/
https://www.ncbi.nlm.nih.gov/pubmed/25295729
http://dx.doi.org/10.1371/journal.pone.0109525