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Role of iron, zinc and reduced glutathione in oxidative stress induction by low pH in rat brain synaptosomes
Brain ischemia leads to a decrease in pH(o). We have shown previously in synaptosomes that the extracellular acidification induces depolarization of mitochondria followed by synthesis of superoxide anions and oxidative stress. Here, we investigated the effects of lowered pH(o) on oxidative stress an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190190/ https://www.ncbi.nlm.nih.gov/pubmed/25332861 http://dx.doi.org/10.1186/2193-1801-3-560 |