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Role of iron, zinc and reduced glutathione in oxidative stress induction by low pH in rat brain synaptosomes

Brain ischemia leads to a decrease in pH(o). We have shown previously in synaptosomes that the extracellular acidification induces depolarization of mitochondria followed by synthesis of superoxide anions and oxidative stress. Here, we investigated the effects of lowered pH(o) on oxidative stress an...

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Detalles Bibliográficos
Autores principales: Pekun, Tatyana G, Hrynevich, Sviatlana V, Waseem, Tatyana V, Fedorovich, Sergei V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190190/
https://www.ncbi.nlm.nih.gov/pubmed/25332861
http://dx.doi.org/10.1186/2193-1801-3-560

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