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Nuclear Ep-ICD accumulation predicts aggressive clinical course in early stage breast cancer patients

BACKGROUND: Regulated intramembrane proteolysis of Epithelial cell adhesion molecule (EpCAM) results in release of its intracellular domain (Ep-ICD) which triggers oncogenic signalling. The clinical significance of Ep-ICD in breast cancer remains to be determined. Herein, we examined the expression...

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Detalles Bibliográficos
Autores principales:	Srivastava, Gunjan, Assi, Jasmeet, Kashat, Lawrence, Matta, Ajay, Chang, Martin, Walfish, Paul G, Ralhan, Ranju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190296/ https://www.ncbi.nlm.nih.gov/pubmed/25265904 http://dx.doi.org/10.1186/1471-2407-14-726

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