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Phosphodiesterase 8a Supports HIV-1 Replication in Macrophages at the Level of Reverse Transcription
BACKGROUND: HIV-1 infected macrophages play a key role in HIV-1 infection. Even during anti-retroviral treatment, macrophages keep producing virus due to suboptimal tissue penetration and reduced efficacy of antiretrovirals. It is therefore of major importance to understand which host factors are in...
Autores principales: | Booiman, Thijs, Cobos Jiménez, Viviana, van Dort, Karel A., van 't Wout, Angélique B., Kootstra, Neeltje A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190361/ https://www.ncbi.nlm.nih.gov/pubmed/25295610 http://dx.doi.org/10.1371/journal.pone.0109673 |
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