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VirS, an OmpR/PhoB subfamily response regulator, is required for activation of vapA gene expression in Rhodococcus equi

BACKGROUND: Rhodococcus equi is an important pulmonary pathogen in foals and in immunocompromised individuals. Virulent R. equi strains carry an 80-90 kb virulence plasmid that expresses the virulence-associated protein A (VapA). VapA expression is regulated by temperature and pH. The LysR-type tran...

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Detalles Bibliográficos
Autores principales: Kakuda, Tsutomu, Hirota, Takuya, Takeuchi, Tatsuya, Hagiuda, Hirofumi, Miyazaki, Shiko, Takai, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190465/
https://www.ncbi.nlm.nih.gov/pubmed/25281192
http://dx.doi.org/10.1186/s12866-014-0243-1