An RNA Aptamer Targets the PDZ-Binding Motif of the HPV16 E6 Oncoprotein

Human papillomavirus 16 (HPV16) is a high-risk DNA tumour virus which is the primary causative agent of cervical cancer. Cell transformation arises from deregulated expression of the E6 and E7 oncogenes. E6 has been shown to bind a number of cellular proteins, including p53 and proteins containing a...

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Detalles Bibliográficos
Autores principales: Belyaeva, Tamara A., Nicol, Clare, Cesur, Özlem, Travé, Gilles, Blair, George Eric, Stonehouse, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190555/
https://www.ncbi.nlm.nih.gov/pubmed/25062098
http://dx.doi.org/10.3390/cancers6031553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190555/
https://www.ncbi.nlm.nih.gov/pubmed/25062098
http://dx.doi.org/10.3390/cancers6031553

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