DNA Mismatch Repair and Oxidative DNA Damage: Implications for Cancer Biology and Treatment

Many components of the cell, including lipids, proteins and both nuclear and mitochondrial DNA, are vulnerable to deleterious modifications caused by reactive oxygen species. If not repaired, oxidative DNA damage can lead to disease-causing mutations, such as in cancer. Base excision repair and nucl...

Descripción completa

Detalles Bibliográficos
Autores principales: Bridge, Gemma, Rashid, Sukaina, Martin, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190558/
https://www.ncbi.nlm.nih.gov/pubmed/25099886
http://dx.doi.org/10.3390/cancers6031597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190558/
https://www.ncbi.nlm.nih.gov/pubmed/25099886
http://dx.doi.org/10.3390/cancers6031597

Ejemplares similares