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DNA Mismatch Repair and Oxidative DNA Damage: Implications for Cancer Biology and Treatment
Many components of the cell, including lipids, proteins and both nuclear and mitochondrial DNA, are vulnerable to deleterious modifications caused by reactive oxygen species. If not repaired, oxidative DNA damage can lead to disease-causing mutations, such as in cancer. Base excision repair and nucl...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190558/ https://www.ncbi.nlm.nih.gov/pubmed/25099886 http://dx.doi.org/10.3390/cancers6031597 |