The Hepatocyte Growth Factor (HGF)/Met Axis: A Neglected Target in the Treatment of Chronic Myeloproliferative Neoplasms?

Met is the receptor of hepatocyte growth factor (HGF), a cytoprotective cytokine. Disturbing the equilibrium between Met and its ligand may lead to inappropriate cell survival, accumulation of genetic abnormalities and eventually, malignancy. Abnormal activation of the HGF/Met axis is established in...

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Detalles Bibliográficos
Autores principales: Boissinot, Marjorie, Vilaine, Mathias, Hermouet, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190560/
https://www.ncbi.nlm.nih.gov/pubmed/25119536
http://dx.doi.org/10.3390/cancers6031631

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