Disease variants in genomes of 44 centenarians

To identify previously reported disease mutations that are compatible with extraordinary longevity, we screened the coding regions of the genomes of 44 Ashkenazi Jewish centenarians. Individual genome sequences were generated with 30× coverage on the Illumina HiSeq 2000 and single-nucleotide variant...

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Detalles Bibliográficos
Autores principales: Freudenberg-Hua, Yun, Freudenberg, Jan, Vacic, Vladimir, Abhyankar, Avinash, Emde, Anne-Katrin, Ben-Avraham, Danny, Barzilai, Nir, Oschwald, Dayna, Christen, Erika, Koppel, Jeremy, Greenwald, Blaine, Darnell, Robert B, Germer, Soren, Atzmon, Gil, Davies, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190879/
https://www.ncbi.nlm.nih.gov/pubmed/25333069
http://dx.doi.org/10.1002/mgg3.86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190879/
https://www.ncbi.nlm.nih.gov/pubmed/25333069
http://dx.doi.org/10.1002/mgg3.86

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