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Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis

Inactivation of tumour suppressor genes by promoter methylation plays an important role in the initiation and progression of gastric cancer (GC). Transmembrane 106A gene (TMEM106A) encodes a novel protein of previously unknown function. This study analysed the biological functions, epigenetic change...

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Detalles Bibliográficos
Autores principales: Xu, Dong, Qu, Liujing, Hu, Jia, Li, Ge, Lv, Ping, Ma, Dalong, Guo, Mingzhou, Chen, Yingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190911/
https://www.ncbi.nlm.nih.gov/pubmed/24975047
http://dx.doi.org/10.1111/jcmm.12352