Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury☆

This study used electroacupuncture at Renzhong (DU26) and Baihui (DU20) in a rat model of cerebral ischemia/reperfusion injury. Neurological deficit scores, western blotting, and reverse transcription-PCR results demonstrated that electroacupuncture markedly reduced neurological deficits, decreased...

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Detalles Bibliográficos
Autores principales: Peng, Yongjun, Wang, Hesheng, Sun, Jianhua, Chen, Li, Xu, Meijuan, Chu, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acupuncture and Moxibustion and Neural Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190948/
https://www.ncbi.nlm.nih.gov/pubmed/25317142
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.36.007
Descripción
Sumario:This study used electroacupuncture at Renzhong (DU26) and Baihui (DU20) in a rat model of cerebral ischemia/reperfusion injury. Neurological deficit scores, western blotting, and reverse transcription-PCR results demonstrated that electroacupuncture markedly reduced neurological deficits, decreased corpus striatum aquaporin-4 protein and mRNA expression, and relieved damage to the blood-brain barrier in a rat model of cerebral ischemia/reperfusion injury. These results suggest that electroacupuncture most likely protects the blood-brain barrier by regulating aquaporin-4 expression following cerebral ischemia/reperfusion injury.

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