Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury☆

This study used electroacupuncture at Renzhong (DU26) and Baihui (DU20) in a rat model of cerebral ischemia/reperfusion injury. Neurological deficit scores, western blotting, and reverse transcription-PCR results demonstrated that electroacupuncture markedly reduced neurological deficits, decreased...

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Autores principales: Peng, Yongjun, Wang, Hesheng, Sun, Jianhua, Chen, Li, Xu, Meijuan, Chu, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acupuncture and Moxibustion and Neural Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190948/
https://www.ncbi.nlm.nih.gov/pubmed/25317142
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.36.007
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author Peng, Yongjun
Wang, Hesheng
Sun, Jianhua
Chen, Li
Xu, Meijuan
Chu, Jihong
author_facet Peng, Yongjun
Wang, Hesheng
Sun, Jianhua
Chen, Li
Xu, Meijuan
Chu, Jihong
author_sort Peng, Yongjun
collection PubMed
description This study used electroacupuncture at Renzhong (DU26) and Baihui (DU20) in a rat model of cerebral ischemia/reperfusion injury. Neurological deficit scores, western blotting, and reverse transcription-PCR results demonstrated that electroacupuncture markedly reduced neurological deficits, decreased corpus striatum aquaporin-4 protein and mRNA expression, and relieved damage to the blood-brain barrier in a rat model of cerebral ischemia/reperfusion injury. These results suggest that electroacupuncture most likely protects the blood-brain barrier by regulating aquaporin-4 expression following cerebral ischemia/reperfusion injury.
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spelling pubmed-41909482014-10-14 Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury☆ Peng, Yongjun Wang, Hesheng Sun, Jianhua Chen, Li Xu, Meijuan Chu, Jihong Neural Regen Res Acupuncture and Moxibustion and Neural Regeneration This study used electroacupuncture at Renzhong (DU26) and Baihui (DU20) in a rat model of cerebral ischemia/reperfusion injury. Neurological deficit scores, western blotting, and reverse transcription-PCR results demonstrated that electroacupuncture markedly reduced neurological deficits, decreased corpus striatum aquaporin-4 protein and mRNA expression, and relieved damage to the blood-brain barrier in a rat model of cerebral ischemia/reperfusion injury. These results suggest that electroacupuncture most likely protects the blood-brain barrier by regulating aquaporin-4 expression following cerebral ischemia/reperfusion injury. Medknow Publications & Media Pvt Ltd 2012-12-25 /pmc/articles/PMC4190948/ /pubmed/25317142 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.36.007 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Acupuncture and Moxibustion and Neural Regeneration
Peng, Yongjun
Wang, Hesheng
Sun, Jianhua
Chen, Li
Xu, Meijuan
Chu, Jihong
Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury☆
title Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury☆
title_full Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury☆
title_fullStr Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury☆
title_full_unstemmed Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury☆
title_short Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury☆
title_sort electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury☆
topic Acupuncture and Moxibustion and Neural Regeneration
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190948/
https://www.ncbi.nlm.nih.gov/pubmed/25317142
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.36.007
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