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Development of non-viral vehicles for targeted gene transfer into microglia via the integrin receptor CD11b

Microglial activation is a central event in neurodegeneration. Novel technologies are sought for that specifically manipulate microglial function in order to delineate their role in onset and progression of neuropathologies. We investigated for the first time whether non-viral gene delivery based on...

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Detalles Bibliográficos
Autores principales: Smolny, Markus, Rogers, Mary-Louise, Shafton, Anthony, Rush, Robert A., Stebbing, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191133/
https://www.ncbi.nlm.nih.gov/pubmed/25346658
http://dx.doi.org/10.3389/fnmol.2014.00079