Ontogeny of Intestinal Epithelial Innate Immune Responses

Emerging evidence indicates that processes during postnatal development might significantly influence the establishment of mucosal host-microbial homeostasis. Developmental and adaptive immunological processes but also environmental and microbial exposure early after birth might thus affect disease...

Descripción completa

Detalles Bibliográficos
Autores principales: Hornef, Mathias W., Fulde, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191320/
https://www.ncbi.nlm.nih.gov/pubmed/25346729
http://dx.doi.org/10.3389/fimmu.2014.00474
Descripción
Sumario:Emerging evidence indicates that processes during postnatal development might significantly influence the establishment of mucosal host-microbial homeostasis. Developmental and adaptive immunological processes but also environmental and microbial exposure early after birth might thus affect disease susceptibility and health during adult life. The present review aims at summarizing the current understanding of the intestinal epithelial innate immune system and its developmental and adaptive changes after birth.

Ejemplares similares