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The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain

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Viral RNA-dependent RNA polymerases (RdRps) responsible for the replication of single-strand RNA virus genomes exert their function in the context of complex replication machineries. Within these replication complexes the polymerase activity is often highly regulated by RNA elements, proteins or oth...

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Detalles Bibliográficos
Autores principales:	Potisopon, Supanee, Priet, Stéphane, Collet, Axelle, Decroly, Etienne, Canard, Bruno, Selisko, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191377/ https://www.ncbi.nlm.nih.gov/pubmed/25209234 http://dx.doi.org/10.1093/nar/gku666

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