Invincible DNA tethers: covalent DNA anchoring for enhanced temporal and force stability in magnetic tweezers experiments

Magnetic tweezers are a powerful single-molecule technique that allows real-time quantitative investigation of biomolecular processes under applied force. High pulling forces exceeding tens of picoNewtons may be required, e.g. to probe the force range of proteins that actively transcribe or package...

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Detalles Bibliográficos
Autores principales: Janissen, Richard, Berghuis, Bojk A., Dulin, David, Wink, Max, van Laar, Theo, Dekker, Nynke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191378/
https://www.ncbi.nlm.nih.gov/pubmed/25140010
http://dx.doi.org/10.1093/nar/gku677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191378/
https://www.ncbi.nlm.nih.gov/pubmed/25140010
http://dx.doi.org/10.1093/nar/gku677

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