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Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4)
Recent small RNA sequencing data has uncovered 3′ end modification of mature microRNAs (miRNAs). This non-templated nucleotide addition can impact miRNA gene regulatory networks through the control of miRNA stability or by interfering with the repression of target mRNAs. The miRNA modifying enzymes...
Autores principales: | Thornton, James E., Du, Peng, Jing, Lili, Sjekloca, Ljiljana, Lin, Shuibin, Grossi, Elena, Sliz, Piotr, Zon, Leonard I., Gregory, Richard I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191393/ https://www.ncbi.nlm.nih.gov/pubmed/25223788 http://dx.doi.org/10.1093/nar/gku805 |
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